BEST Endovascular Versus Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST-CLI) Trial

Design and Rationale of the Best Endovascular Versus Best Surgical Therapy for Patients With Critical Limb Ischemia (BEST‐CLI) Trial

BACKGROUND Critical limb ischemia (CLI) is increasing in prevalence, and remains a significant source of mortality and limb loss. The decision to recommend surgical or endovascular revascularization for patients who are candidates for both varies significantly among providers and is driven more by individual preference than scientific evidence. METHODS AND RESULTS The Best Endovascular Versus...

Vagus nerve stimulation versus “best drug therapy” in epilepsy patients who have failed best drug therapy

Vagus nerve stimulation versus ''best drug therapy'' in epilepsy patients who have failed best drug therapy I would like to thank Dr. Hoppe and colleagues for their recent study published in Seizure examining vagus nerve stimulation (VNS) versus ''best drug therapy'' in medically refractory epilepsy patients. 1 However, I have concerns regarding the authors' methodology and conclusions. In this...

Best Approximation in TVS

In this paper  we give newresults on the best approximation  in the Hausdorff topological vectorspace and  consider relationship  with orthogonality. Also we determined under  what conditions the map $P_{K,f}$ is upper semicontinous.

Best surgical option for thoracoabdominal aneurysm repair - the endovascular approach.

Management of Critical Limb Ischemia.

Critical limb ischemia (CLI) is a clinical syndrome of ischemic pain at rest or tissue loss, such as nonhealing ulcers or gangrene, related to peripheral artery disease. CLI has a high short-term risk of limb loss and cardiovascular events. Noninvasive or invasive angiography help determine the feasibility and approach to arterial revascularization. An endovascular-first approach is often advoc...